Instead of the basic A, C, E, selenium combination, Anti-Oxidant provides nutrients that support the body during liver and systemic detoxification. Vitamin C, thiamine, riboflavin, niacin, vitamin B6, pantothenic acid, zinc, and selenium work collectively as cofactors in many enzyme systems to support metabolism and detoxification. Vitamin C directly protects fat-soluble vitamins A and E and some B vitamins from oxidation.

A number of amino acids and other organic acids are essential for detoxification of free radicals. Research on dimethylglycine has demonstrated its ability to enable tissues to improve oxygen utilization, ultimately protecting the body from free radical damage created by stress. N-acetylcysteine replenishes the body's glutathione levels by providing the rate-limiting substrate (cysteine) for glutathione synthesis. Glutamic acid is converted in the body to glutathione and glutamine and is most helpful in clearing potentially toxic ammonia by-products. Alpha-lipoic acid is a readily absorbed antioxidant that exerts its action in both fat-soluble and water-soluble tissues. Anti-Oxidant provides lipoic acid in the all-natural, most bioavailable form – R-lipoic acid. Reduced glutathione (GSH) is an essential cofactor for many detoxification and antioxidant enzyme systems. In addition to the potent antioxidant capacity of glutathione, GSH status in the body is a highly sensitive indicator of cell function and viability. Glycine is an important amino acid, supporting liver detoxification and enhancing the body's glutathione stores.